NCT06715046View on ClinicalTrials.gov

Cell Free DNA Profiling As a Tool to Monitor Clinically-Relevant Events in Allogeneic Hematopoietic Stem Cell Transplantation

RecruitingOBSERVATIONAL
Enrollment

30

Participants

Timeline

Start Date

January 31, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
GVHD - Graft-Versus-Host DiseaseInfections After HSCTTransplant Associated Microangiopathy TAMSinusoidal Obstruction Syndrome (SOS)HSCT Engraftment
Interventions
DIAGNOSTIC_TEST

Sample collation for cfDNA methylation analysis

Sample collation for cfDNA methylation analysis

DIAGNOSTIC_TEST

Sample collection for EV phenotype analysis

Analysis of the EV phenotype to evaluate their potential value as markers for GVHD, relapse and engraftment.

Trial Locations (2)

10126

RECRUITING

SS Trapianto allogenico e terapie cellulari, SC Ematologia U of the Città della Salute e della Scienza Hospital, Turin

10132

RECRUITING

Unità di Ematologia e Trapianto di Midollo Osseo e Oncoematologia of the San Raffaele Hospital in Milan, Milan

All Listed Sponsors
collaborator

IRCCS San Raffaele

OTHER

lead

University of Turin, Italy

OTHER