NCT06714253View on ClinicalTrials.gov

Study of Circular RNA Treatment in Patients With Radiation Induced Xerostomia-1

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

42

Participants

Timeline

Start Date

March 5, 2025

Primary Completion Date

August 31, 2027

Study Completion Date

August 31, 2027

Conditions
Radiation-Induced Xerostomia and Hyposalivation
Interventions
BIOLOGICAL

RXRG001

Circular ribonucleic acid encoding human aquaporin 1 encapsulated in a lipid nanoparticle

BIOLOGICAL

Placebo

Placebo (saline)

Trial Locations (3)

19104

RECRUITING

Penn Medicine - Otorhinolaryngology - Head and Neck Surgery Perelman, Philadelphia

21287

RECRUITING

John Hopkins University, Sidney Kimmel Comprehensive Cancer Center, Baltimore

52242

RECRUITING

University of Iowa Hospitals and Clinics, Iowa City

All Listed Sponsors
lead

RiboX Therapeutics Ltd.

INDUSTRY