Investigation of Drug-drug Interaction of Ritonavir and Itraconazole on the Pharmacokinetics of SHR-A1811 in Subjects With HER2-expressing Advanced Breast Cancer

PHASE1RecruitingINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

February 17, 2025

Primary Completion Date

June 30, 2025

Study Completion Date

August 31, 2026

Conditions

Advanced Breast Cancer

Interventions

DRUG

SHR-A1811

DRUG

Ritonavir

DRUG

Itraconazole

Trial Locations (2)

RECRUITING

Hunan Cancer Hospital, Changsha

RECRUITING

Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou

All Listed Sponsors

lead

Jiangsu HengRui Medicine Co., Ltd.

INDUSTRY