Thermal Ablation Versus Parathyroidectomy for Secondary Hyperparathyroidism

Not yet recruitingOBSERVATIONAL
Enrollment

612

Participants

Timeline

Start Date

November 26, 2024

Primary Completion Date

November 26, 2028

Study Completion Date

December 30, 2028

Conditions
Achievement RateEfficacy and SafetyPTHCalciumClinical Symptoms
Interventions
PROCEDURE

Thermal ablation

Thermal ablation is a treatment for secondary hyperparathyroidism. There are radiofrequency ablation (RFA) and microwave ablation (MWA). For RFA, an electrode needle is inserted into the parathyroid under imaging guidance. High - frequency current heats the tissue to cause necrosis. MWA uses electromagnetic waves to generate heat by friction. Before ablation, imaging and lab tests are done for evaluation. During the process, precise positioning and real - time monitoring are key. After that, patients are observed for bleeding, swelling and other symptoms, and tests are repeated to assess the effect.

PROCEDURE

parathyroidectomy

Parathyroidectomy for secondary hyperparathyroidism is a common approach. The surgeon first makes an incision in the neck area under general or local anesthesia. Then, the enlarged parathyroid glands are carefully identified and dissected. Precise surgical skills are required to avoid damaging nearby structures such as the recurrent laryngeal nerve and blood vessels. After the removal of the abnormal parathyroid tissue, the wound is closed.

All Listed Sponsors
lead

Chinese PLA General Hospital

OTHER

NCT06709586 - Thermal Ablation Versus Parathyroidectomy for Secondary Hyperparathyroidism | Biotech Hunter | Biotech Hunter