NCT06705010View on ClinicalTrials.gov

Monitoring of Brain Metabolites Using Proton and Deuterium MR Techniques

NANot yet recruitingINTERVENTIONAL
Enrollment

140

Participants

Timeline

Start Date

April 1, 2025

Primary Completion Date

November 1, 2026

Study Completion Date

March 31, 2028

Conditions
AgingBrain Metabolic DisorderCarotid StenosisAlzheimer DiseaseDiabetes Type 2Mild Cognitive ImpairmentBrain Disease
Interventions
DEVICE

Application of new pulse sequence package SIGNATURES2023 to healthy controls

One or more novel or further optimized non CE-marked pulse MRSI sequence is/are applied to 100 healthy subjects to determined reference metabolite maps of the whole brain

DEVICE

Application of new pulse sequence package SIGNATURES2023 to 4 groups of patients (pilot)

One or more novel or further optimized non CE-marked pulse MRSI sequence is/are applied to 4 time 10 patients with AD, MCI, DM and HGCS to determine metabolite maps of the whole brain.

Trial Locations (1)

3010

Translational Imaging Center / Sitem, Bern

All Listed Sponsors
lead

Insel Gruppe AG, University Hospital Bern

OTHER