Gene Modulation of NLRP3, IL-1β and TNF-α in Peripheral Blood of Patients With Exogenous Obesity Treated With Berberine

NACompletedINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

January 5, 2019

Primary Completion Date

August 15, 2019

Study Completion Date

February 15, 2020

Conditions
ObesityOverweightBerberine
Interventions
DIETARY_SUPPLEMENT

Berberine Hydrochloride group

The patient will be given a nutritional plan, moderate aerobic exercise with a goal of 10,000 steps or 150 min per week; and the phytopharmaceutical Berberine will be taken 3 tablets ( 500 mg) every 8 hours for 3 months.

BEHAVIORAL

nutritional plan

nutritional plan according to your caloric requirements for lifestyle change and you will be scheduled biweekly for 3 months

BEHAVIORAL

controlled moderate aerobic exercise

controlled moderate aerobic exercise that will consist of a goal of 10,000 steps or 150 minutes per week.

All Listed Sponsors
lead

National Polytechnic Institute, Mexico

OTHER

NCT06703086 - Gene Modulation of NLRP3, IL-1β and TNF-α in Peripheral Blood of Patients With Exogenous Obesity Treated With Berberine | Biotech Hunter | Biotech Hunter