Enhanced Problem-solving Therapy and HIV Engagement Support to Improve Perinatal Mental Health & HIV Outcomes in Malawi

NARecruitingINTERVENTIONAL
Enrollment

400

Participants

Timeline

Start Date

February 26, 2025

Primary Completion Date

June 30, 2028

Study Completion Date

June 30, 2028

Conditions
HIVDepressionDepression, Postpartum
Interventions
BEHAVIORAL

Enhanced Friendship Bench

Friendship Bench problem-solving therapy involving 4 prenatal and 2 postnatal counseling sessions, enhanced for HIV care engagement with 2 social support building sessions and monthly home visits for ART delivery and counseling during the 3rd trimester and the first 3 months postpartum.

BEHAVIORAL

Enhanced usual care

Usual care for mental health in public facilities in Malawi includes options for basic supportive counseling by a primary provider or nurse, medication management by the primary provider (amitriptyline is the one antidepressant typically available at primary health centers and is rarely prescribed for depression), referral to the clinic psychiatric nurse or mental health clinic, or in more severe cases referral to the psychiatric units at tertiary care hospitals. For the proposed study, usual care will be enhanced to provide a mental health evaluation; brief supportive counseling; information, education, and support on common mental disorders; and (if indicated) facilitation of referral for further follow-up at a mental health clinic or psychiatric unit.

Trial Locations (5)

Unknown

NOT_YET_RECRUITING

Area 18 Health Center, Lilongwe

RECRUITING

Area 25 Health Center, Lilongwe

RECRUITING

Bwaila Hospital, Lilongwe

RECRUITING

Kawale Health Center, Lilongwe

RECRUITING

Likuni Mission Hosptial, Lilongwe

All Listed Sponsors
collaborator

National Institute of Mental Health (NIMH)

NIH

lead

University of North Carolina, Chapel Hill

OTHER