80
Participants
Start Date
December 13, 2021
Primary Completion Date
December 31, 2025
Study Completion Date
December 31, 2025
Rotational Therapy
Sample1- Ventilator settings where adjusted with PEEP based on BMI, followed by a 2 cmH2O increase and 20 minutes in a lateral position at 30 degrees for lung recruitment for both sides. And at the end were subjected to an alveolar recruitment maneuver with pressure increases up to a plateau pressure of 45 cmH2O. Sample2- A recruitment maneuver followed by PEEP titration is performed, selecting the PEEP that is above the crossing point between the collapse and hyperdistension curves provided by EIT. And the the PEEP-ARDSNet will be selected according to the low PEEP-FIO2 table from the ARDSNet protocol. Observations are made at 4 and 24 hours, with PEEP at 24 hours adjusted to the level identified by EIT.
Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da USP, São Paulo
University of Sao Paulo General Hospital
OTHER