75
Participants
Start Date
March 22, 2025
Primary Completion Date
November 30, 2026
Study Completion Date
November 30, 2026
Emapalumab-Izsg
The drug is administered at a dose of 6mg/kg of body weight on day 0 and repeated dosing of 3mg/kg of body weight is provisioned for days 3, 6, 9, 12, 15, 19, 23 and 27 provided that the stopping rule does not apply.
Emapalumab-Izsg
The drug is administered at a dose of 6mg/kg of body weight on day 0, 6mg/kg of body weight on day 3, 6mg/kg of body weight on day 6 and repeated dosing of 3mg/kg of body weight is provisioned for days 9, 12, 15, 19, 23 and 27 provided that the stopping rule does not apply.
Placebo
250ml of 0.9% sodium chloride. The drug is administered on day 0 and repeated dosing is provisioned for days 3, 6, 9, 12, 15, 19, 23 and 27 provided that the stopping rule does not apply
RECRUITING
1st Department of Internal Medicine, Thriasio Elefsis General Hospital, Elefsina
RECRUITING
Clinic of Intensive Care and Pulmonary Diseases, Aghioi Anargyroi Kifissia General Oncologic Hospital, Kifissia
RECRUITING
Intensive Care Unit, Herakleion University General Hospital, Heraklion
RECRUITING
Intensive Care Unit, Alexandroupolis University General Hospital, Alexandroupoli
RECRUITING
3rd University Department of Internal Medicine, Sotiria Chest Diseases Athens General Hospital, Athens
RECRUITING
4th Department of Internal Medicine, ATTIKON University General Hospital, Athens
RECRUITING
Intensive Care Unit I, KAT Attica General Hospital, Athens
RECRUITING
Intensive Care Unit of 1st University Department Respiratory Medicine, Sotiria Chest Diseases Athens General Hospital, Athens
RECRUITING
Intensive Care Unit of Center for Respiratory Failure, Sotiria Chest Diseases Athens General Hospital, Athens
RECRUITING
Intensive Care Unit, Asklipieio Voulas General Hospital, Athens
RECRUITING
Intensive Care Unit, Ippokrateio Athens General Hospital, Athens
RECRUITING
Intensive Care Unit, Korgialeneio-Benakeio HRC Athens General Hospital, Athens
RECRUITING
Intensive Care Unit, Laiko Athens General Hospital, Athens
RECRUITING
New Multivalent Intensive Care Unit, Sotiria Chest Diseases Athens General Hospital, Athens
RECRUITING
Ηigh Dependency Unit of Department of Clinical Therapeutics, Alexandra Athens General Hospital, Athens
RECRUITING
Intensive Care Unit, Patras University General Hospital, Pátrai
RECRUITING
1st Intensive Care Unit, G. Papanikolaou Thessaloniki General Hospital, Thessaloniki
RECRUITING
Department of Anesthesiology and Intensive Care, AHEPA Thessaloniki University General Hospital, Thessaloniki
NOT_YET_RECRUITING
Intensive Care Unit, 424 General Military Training Hospital, Thessaloniki
RECRUITING
Intensive Care Unit, Aghios Dimitrios Thessaloniki General Hospital, Thessaloniki
RECRUITING
Intensive Care Unit, G. Gennimatas Thessaloniki General Hospital, Thessaloniki
RECRUITING
Intensive Care Unit, Ippokrateio Thessaloniki General Hospital, Thessaloniki
RECRUITING
Intensive Care Unit, Papageorgiou Thessaloniki General Hospital, Thessaloniki
RECRUITING
Intensive Care Unit, Theageneio Thessaloniki Cancer Hospital, Thessaloniki
Hellenic Institute for the Study of Sepsis
OTHER