Evaluating the Pharmacokinetics of Oregano and Potential Oregano-drug Interactions Using a Drug Cocktail Approach

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

16

Participants

Timeline

Start Date

September 26, 2024

Primary Completion Date

September 15, 2025

Study Completion Date

December 31, 2025

Conditions
Interaction
Interventions
DIETARY_SUPPLEMENT

Oregano

Oil of oregano administered as a softgel (180 mg).

DRUG

Drug cocktail

Oral drug cocktail consisting of caffeine (100 mg), dextromethorphan (30 mg), losartan (25 mg), midazolam syrup (2 mg), and omeprazole (20 mg).

Trial Locations (1)

99202

RECRUITING

Washington State University College of Pharmacy and Pharmaceutical Sciences, Spokane

All Listed Sponsors
collaborator

Office of Dietary Supplements (ODS)

NIH

collaborator

National Center for Complementary and Integrative Health (NCCIH)

NIH

lead

Washington State University

OTHER