STOP-UC: De-escalation of Therapy in Patients With Ulcerative Colitis With Histological Remission

NANot yet recruitingINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

October 31, 2025

Primary Completion Date

October 31, 2026

Study Completion Date

October 31, 2027

Conditions
Ulcerative Colitis (UC)
Interventions
OTHER

de-escalation or discontinuation of therapy

De-escalation of therapy, defined as a step-down from maintenance with advanced therapy (biologic or synthetic small molecule) to oral aminosalicylate-based therapy or complete discontinuation of therapy if they are allergic or intolerant to aminosalicylate-based therapy. If patients are receiving immunomodulator or oral aminosalicylate maintenance therapy, they will be de-escalated to complete discontinuation of therapy.

OTHER

continuation of current therapy

continuation of current maintenance medical therapy for ulcerative colitis

Trial Locations (1)

60637

University of Chicago, Chicago

All Listed Sponsors
lead

University of Chicago

OTHER

NCT06693310 - STOP-UC: De-escalation of Therapy in Patients With Ulcerative Colitis With Histological Remission | Biotech Hunter | Biotech Hunter