Improving 24-hour Blood Pressure Stability in Spinal Cord Injury with Low Oxygen Therapy

PHASE1/PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

February 28, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Spinal Cord Injury
Interventions
OTHER

Low oxygen therapy (LOT)

"Participants will breathe variable concentrations of inspired oxygen, carbon dioxide, and nitrogen. The concentrations will be adjusted on a breath-by-breath basis to maintain end-tidal targets.~Each daily session of the intervention will consist of forty 1-minute intervals. Each 1-minute interval will consist of 40 seconds of hypercapnic hypoxia, increasing the partial pressure of end-tidal carbon dioxide by +4 mmHg and decreasing the partial pressure of end-tidal oxygen to 45 mmHg, followed by 20 seconds in simulated room air to return to baseline carbon dioxide and oxygen levels."

All Listed Sponsors
lead

Glen Foster

OTHER

NCT06691165 - Improving 24-hour Blood Pressure Stability in Spinal Cord Injury with Low Oxygen Therapy | Biotech Hunter | Biotech Hunter