Detection of Sepsis Occurrence by Using Blood Fluorescence

RecruitingOBSERVATIONAL
Enrollment

800

Participants

Timeline

Start Date

January 24, 2024

Primary Completion Date

October 1, 2026

Study Completion Date

October 1, 2027

Conditions
SepsisOrgan Damage
Interventions
OTHER

Blood fluorescence metabolite analysis

This is an observational study and does not involve intervention. In both the early and late stages of sepsis, a significant increase in inflammatory free radicals changes the optical properties of the patient\'s blood, distinguishing it from that of healthy individuals. To explore this phenomenon, 4 cc of fasting blood is drawn from patients who pass our screening criteria. This sample is then centrifuged in accordance with our detailed standard operating procedures to ready it for analysis. Subsequently, the fluorescence intensity of the blood is measured quantitatively using a precisely calibrated blood fluorometer, which is specifically designed to detect subtle variations indicative of both early and late sepsis. This entire process is executed under stringent quality control protocols to ensure the reliability and accuracy of the results, which are pivotal for the timely diagnosis and intervention in septic patients.

Trial Locations (1)

315010

RECRUITING

Ningbo Institute of Innovation for Combined Medicine and Engineering (NIIME), Ningbo Medical Center Lihuili Hospital, Ningbo University, Ningbo

All Listed Sponsors
collaborator

University of Macau

OTHER

lead

Ningbo Medical Center Lihuili Hospital

OTHER_GOV