NCT06688786View on ClinicalTrials.gov

A Pospective, Single-arm, Multicenter Clinical Trial Evaluating Preoperative Neoadjuvant mFOLFOX6 Chemotherapy in Combination With PD1 Monoclonal Antibody in MSS/pMMR Locally Advanced Rectal Cancer

NARecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

November 1, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2027

Conditions
Locally Advanced Rectal Cancer (LARC)
Interventions
DRUG

neoadjuvant mFOLFOX6 chemotherapy combined with PD-1 inhibitor therapy

Preoperative treatment with 4-6 cycles of mFOLFOX6 regimen combined with serplulimab

Trial Locations (1)

200092

RECRUITING

Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai

All Listed Sponsors
lead

Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

OTHER