Minimally Invasive Soft Channel Brain Haemorrhage Evacuation for Acute Basal Ganglia Haemorrhage-- Large Hemorrhage Evacuation (MIRACLE-L)

NARecruitingINTERVENTIONAL
Enrollment

550

Participants

Timeline

Start Date

January 4, 2025

Primary Completion Date

November 30, 2026

Study Completion Date

December 31, 2026

Conditions
Intracerebral Hemorrhage
Interventions
OTHER

Other neurosurgical techniques

Those include open craniotomy, small skull window microsurgery, and endoscopic surgery. The attending clinician is required to consider which type of craniotomy or other procedure according to the expertise and availability at the hospital.

PROCEDURE

Minimally Invasive Soft Channel Brain Haemorrhage Evacuation

This technique is based on the study of hematoma anatomy, cerebral vascular anatomy, and neural fiber structure anatomy in basal ganglia hemorrhage to determine the optimal surgical (catheter insertion) path. By applying stereogeometric principles, it allows for simple yet precise localization. Through surgical steps including puncture, aspiration, liquefaction (intermittent infusion of urokinase or alteplase), and external drainage, the hematoma can be completely removed in stages over a short period. This ensures that hematoma clearance and decompression of the brain occur simultaneously, achieving a minimally invasive intracerebral hemorrhage evacuation technique with a gradual reduction in intracranial pressure.

Trial Locations (1)

276000

RECRUITING

Linyi People's Hospital, Linyi

All Listed Sponsors
collaborator

Linyi People's Hospital

OTHER

collaborator

Fudan University

OTHER

lead

Capital Medical University

OTHER