Minimally Invasive Soft Channel Brain Haemorrhage Evacuation for Acute Basal Ganglia Haemorrhage--Small Hemorrhage Evacuation (MIRACLE-S)

NAEnrolling by invitationINTERVENTIONAL
Enrollment

750

Participants

Timeline

Start Date

January 16, 2025

Primary Completion Date

November 30, 2026

Study Completion Date

December 30, 2026

Conditions
Intracerebral Hemorrhage
Interventions
OTHER

Usual Care

During the study treatment and follow-up periods, patients are to receive usual standard of care according to published guidelines for acute stroke care. It is anticipated that background care may include the use of other treatments including drugs and interventions.

PROCEDURE

Minimally Invasive Soft Channel Brain Haemorrhage Evacuation (scMIS)

This technique is based on the study of hematoma anatomy, cerebral vascular anatomy, and neural fiber structure anatomy in basal ganglia hemorrhage to determine the optimal surgical (catheter insertion) path. By applying stereogeometric principles, it allows for simple yet precise localization. Through surgical steps including puncture, aspiration, liquefaction (intermittent infusion of urokinase or alteplase), and external drainage, the hematoma can be completely removed in stages over a short period. This ensures that hematoma clearance and decompression of the brain occur simultaneously, achieving a minimally invasive intracerebral hemorrhage evacuation technique with a gradual reduction in intracranial pressure.

Trial Locations (1)

Unknown

Capital Medical University, Beijing

All Listed Sponsors
collaborator

Fudan University

OTHER

collaborator

Linyi People's Hospital

OTHER

lead

Capital Medical University

OTHER