Nasal High Frequency in Preterm Neonates

NACompletedINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

July 15, 2021

Primary Completion Date

July 15, 2022

Study Completion Date

July 15, 2023

Conditions
Respiratory Distress Syndrome (RDS)Neonatal Diseases and Abnormalities
Interventions
DEVICE

nasal high frequency oscillatory ventilation mode

"Preterm neonates who will be allocated will start nHFOV: (CNO, Medin, Germany). nHFOV will be provided via binasal prongs (Size: small, medium, large; Diameter according to its chart; Medin, Germany).~The initial parameters will be mean airway pressure (MAP) of 6 cm H2O (range 6-10), frequency of 8 Hz (range 8-12) and amplitude will be adjusted until infant's chest showed slight oscillations and amplitude will be 7 (range 7-10).~The fraction of inspired oxygen (FiO2) will be adjusted to maintain target oxygen saturation (SpO2) from 92% to 95% by a pulse oximeter."

DRUG

nasal continuous positive pressure ventilation mode

Preterm neonates who will be allocated to this group to the nCPAP will be started on a pressure of 6-8 cm H2O, FiO2) will be adjusted to maintain target oxygen saturation (SpO2) from 92% to 95% by a pulse oximeter

Trial Locations (1)

Unknown

Ain Shams University, Cairo

All Listed Sponsors
lead

Ain Shams University

OTHER

NCT06687083 - Nasal High Frequency in Preterm Neonates | Biotech Hunter | Biotech Hunter