35
Participants
Start Date
October 9, 2024
Primary Completion Date
October 1, 2026
Study Completion Date
October 1, 2029
Neoadjuvant chemotherapy combined with Toripalimab
"1, Neoadjuvant Chemotherapy Phase Combined with Toripalimab~1. First Phase of Neoadjuvant Chemotherapy: Epirubicin + Cyclophosphamide + Toripalimab. Administered intravenously: 100 mg/m² Epirubicin + 600 mg/m² Cyclophosphamide + 240 mg Toripalimab, every 3 weeks for a total of 6 weeks.~2. Second Phase of Neoadjuvant Chemotherapy: Albumin-bound Paclitaxel + Toripalimab. Administered intravenously: 260 mg/m² Albumin-bound Paclitaxel + 240 mg Toripalimab, every 3 weeks for a total of 6 weeks.~2, Receive Breast Cancer Radical Surgery After 4 Cycles of Neoadjuvant Chemotherapy 3, Postoperative Adjuvant Therapy~1. If pathology indicates pCR: Continue immunotherapy, administering 240 mg Toripalimab intravenously every 3 weeks for a total of 1 year.~2. If pathology indicates non-PCR: Continue postoperative adjuvant chemotherapy combined with Toripalimab.~4, Perform Gene Testing on Biopsy Tissue Before Treatment, and Collect Blood Samples for ctDNA Testing Before and After Treatment."
NOT_YET_RECRUITING
Nanchang People's Hospital, Nanchang
RECRUITING
The First Affiliated Hospital of Anhui Medical University, Anhui
RECRUITING
Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou
RECRUITING
The First Affiliated Hospital of Zhejiang University, Hangzhou
RECRUITING
Zhejiang Cancer Hospital, Hangzhou
NOT_YET_RECRUITING
Harbin Medical University Cancer Hospital, Harbin
RECRUITING
Jinhua Municipal Central Hospital, Jinhua
RECRUITING
Nantong First People's Hospital, Nantong
RECRUITING
Zhongshan Hospital, Fudan University, Shanghai
NOT_YET_RECRUITING
Shanxi Provincial Cancer Hospital, Shanxi
NOT_YET_RECRUITING
The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an
NOT_YET_RECRUITING
Xinjiang Medical University Affiliated Cancer Hospital, Xinjiang
RECRUITING
The First Affiliated Hospital of Zhengzhou University, Zhengzhou
First Affiliated Hospital of Zhejiang University
OTHER