150
Participants
Start Date
January 17, 2025
Primary Completion Date
September 30, 2026
Study Completion Date
September 30, 2027
NEU-411
NEU-411, a potent, selective, orally bioavailable, highly permeable, brain penetrant, small molecule inhibitor of LRRK2 activity
Placebo
Orally-administered matched placebo
RECRUITING
Icahn School of Medicine at Mount Sinai/Mount Sinai West, New York
RECRUITING
Columbia University, New York
RECRUITING
Northwell Health, Great Neck
RECRUITING
University of Rochester, Rochester
NOT_YET_RECRUITING
Thomas Jefferson University Hospital, Philadelphia
NOT_YET_RECRUITING
Policlinica Gipuzkoa - Centro de Investigacion Parkinson (CIP), San Sebastián
NOT_YET_RECRUITING
IRCCS Ospedale San Raffaele (HSR) - Dipartimento Di Neurologia, Milan
NOT_YET_RECRUITING
University of Maryland, Baltimore
RECRUITING
University of Virginia, Charlottesville
RECRUITING
University of North Carolina - Chapel Hill, Chapel Hill
NOT_YET_RECRUITING
Velocity Clinical Research at Raleigh Neurology, Raleigh
NOT_YET_RECRUITING
Universidad Autonoma de Madrid (UAM) - Hospital Universitario de La Princesa, Madrid
NOT_YET_RECRUITING
Hospital Universitario HM Puerta del Sur, Móstoles
RECRUITING
Medical University of South Carolina, Charleston
RECRUITING
Emory University, Atlanta
RECRUITING
Augusta University, Augusta
RECRUITING
University of Florida, Gainesville
RECRUITING
Neurology One, Orlando
RECRUITING
Parkinson's Disease and Movement Disorders Center of Boca Raton, Boca Raton
RECRUITING
USF Parkinson's & Movement Disorders Clinic, Tampa
NOT_YET_RECRUITING
Universita Degli Studi Di Padova - Azienda Ospedaliera Di Padova - Clinica Neurologica, Padua
RECRUITING
Vanderbilt University, Nashville
RECRUITING
University of Kentucky, Lexington
NOT_YET_RECRUITING
Hospital Universitario Virgen del Rocio (HUVR) - Instituto de Biomedicina de Sevilla (IBIS), Seville
RECRUITING
The Ohio State University, Columbus
RECRUITING
Quest Research Institute, Farmington Hills
NOT_YET_RECRUITING
Instituto de Investigacion Sanitaria Biocruces Bizkaia - Hospital Universitario Cruces, Barakaldo
NOT_YET_RECRUITING
Medical College of Wisconsin, Milwaukee
RECRUITING
Struthers Parkinson Center, Golden Valley
NOT_YET_RECRUITING
Azienda Ospedaliero Universitaria Pisana - Stabilimento Ospedaliero Di Santa Chiara, Pisa
RECRUITING
Northwestern Medical Group, Department of Neurology, Chicago
RECRUITING
University of Kansas Medical Center, Kansas City
NOT_YET_RECRUITING
Ochsner Clinic Foundation, New Orleans
RECRUITING
University of Arkansas, Little Rock
RECRUITING
The Movement Disorder Clinic of Oklahoma, Tulsa
NOT_YET_RECRUITING
Neurology Consultants of Dallas PA, Dallas
RECRUITING
Baylor College of Medicine, Houston
NOT_YET_RECRUITING
The University of Texas Health Science Center at Houston, Houston
RECRUITING
Central Texas Neurology Consultants, Round Rock
RECRUITING
University of Colorado - Anschutz Medical Campus, Aurora
NOT_YET_RECRUITING
"Universita Degli Studi Della Campania Luigi Vanvitelli - Azienda Ospedaliera Universitaria", Napoli
RECRUITING
University of Utah Movement Division, Salt Lake City
RECRUITING
Banner Sun Health Research Institute, Sun City
RECRUITING
Cleveland Clinic, Las Vegas
RECRUITING
University of California, Los Angeles, Los Angeles
NOT_YET_RECRUITING
Esperanza Clinical, Murrieta
RECRUITING
University of California, Irvine, Irvine
RECRUITING
Neuro-Pain Medical Center, Fresno
NOT_YET_RECRUITING
Parkinson's Research Centers of America - Palo Alto, Palo Alto
RECRUITING
Oregon Health & Science University (OHSU), Portland
RECRUITING
EvergreenHealth, Kirkland
NOT_YET_RECRUITING
Invicro, New Haven
RECRUITING
Beth Israel Deaconess Medical Center, Boston
NOT_YET_RECRUITING
Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) - San Raffaele Pisana, Rome
NOT_YET_RECRUITING
Fondazione Policilinico Universitario A Gemelli IRCCS, Rome
NOT_YET_RECRUITING
Centrum Medyczne Neuromed, Bydgoszcz
NOT_YET_RECRUITING
NZOZ Wielospecjalistyczna Poradnia Lekarska Synapsis Lech Szczechowski, Katowice
NOT_YET_RECRUITING
Pro Life Medica Sp. z o. o. ETA Lublin, Lublin
NOT_YET_RECRUITING
Insula Badania Sp. Z o.o., Warsaw
NOT_YET_RECRUITING
Hospital Universitari Vall d'Hebron, Barcelona
NOT_YET_RECRUITING
Hospital Clinic de Barcelona (Hospital Clinic i Provincial) - Barnaclinic S.A., Barcelona
NOT_YET_RECRUITING
St George's Hospital, University of London, London
NOT_YET_RECRUITING
University College London Hospitals NHS Foundation Trust, London
NOT_YET_RECRUITING
Clinical Aging Research Unit, Newcastle University, Newcastle upon Tyne
NOT_YET_RECRUITING
Ninewells Hospital and Medical School - NHS Tayside, Dundee
Lead Sponsor
Qiagen Manchester Limited
UNKNOWN
Roche Diagnostic Ltd.
INDUSTRY
Neuron23 Inc.
INDUSTRY