10
Participants
Start Date
November 22, 2024
Primary Completion Date
July 30, 2025
Study Completion Date
August 30, 2025
iPancreas automated insulin delivery system
The Model Predictive Control (MPC) insulin infusion algorithm contains a model within the controller that takes as an input the aerobic metabolic expenditure in addition to the CGM and meal in puts. The algorithm uses heart rate and accelerometer data collected on the patient's body to calculate metabolic expenditure (METs). The METs then acts on the model for the insulin dynamics, whereby more energy expenditure and longer duration exercise can lead to a more substantial effect of insulin on the CGM. The MPC also has missed meal insulin bolus detection where the system will calculate the amount of insulin that was missed for a meal. The missed meal boluses can be delivered automatically without any input from the user. This feature can also be disabled. The MPC has a new feature called hyperglycemia pattern detection and dosing algorithm that will analyze problem patterns associated with high blood sugar and automatically calculate and deliver a correction dose.
RECRUITING
Oregon Health and Science University, Portland
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Oregon Health and Science University
OTHER