A Multifocal TDCS-EEG Protocol for Improving Symptoms of Mild Cognitive Impairment and Early Dementia

NARecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

October 1, 2024

Primary Completion Date

October 1, 2026

Study Completion Date

October 1, 2026

Conditions
Mild Cognitive Impairment (MCI)DementiaAlzheimer Disease, Early OnsetAlzheimer DiseaseFrontotemporal Degeneration (FTD)Neurocognitive Decline
Interventions
DEVICE

StarStim 32, Neuroelectrics, Spain - Real multifocal tDCS

Real multifocal tDCS will be delivered with an intensity of 2.0 mA over 8 electrodes positioned over the frontal and temporal areas in the left hemisphere according to the international 10/10 EEG system. The overall duration of stimulation will be set at 20 minutes.

DEVICE

StarStim 32, Neuroelectrics, Spain - Sham multifocal tDCS

Sham multifocal tDCS will be delivered with an intensity of 2.0 mA over 8 electrodes positioned over the frontal and temporal areas in the left hemisphere according to the international 10/10 EEG system. The overall duration of stimulation will be set at 30 seconds.

BEHAVIORAL

Cognitive treatment

During the two cycles, all participants will undergo traditional cognitive stimulation therapy, involving paper-and-pencil exercise and computerised activity on several cognitive domains including memory, attention, and executive functions (duration 30-40 minutes) .

Trial Locations (1)

81100

RECRUITING

"Department of Psychology, University of Campania Luigi Vanvitelli", Caserta

All Listed Sponsors
lead

University of Campania Luigi Vanvitelli

OTHER