Ephedrine Doses to Prevent Maternal Hypotension After Spinal Anesthesia in Cesarean Section

PHASE4CompletedINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

August 1, 2020

Primary Completion Date

August 1, 2021

Study Completion Date

February 15, 2022

Conditions
Hypotension After Spinal AnesthesiaHypotension During Cesarean Delivery
Interventions
DRUG

Normal Saline (Placebo)

Participants in the control group receive a continuous intravenous infusion of normal saline, which serves as an inert placebo with no pharmacological effect. This intervention mimics the administration of the active treatments, allowing for direct comparison with the ephedrine groups to assess the effectiveness of the drug in preventing maternal hypotension during spinal anesthesia.

DRUG

Ephedrine

The interventions in this study include a control group receiving normal saline, which serves as an inert placebo to assess the effectiveness of the active treatments. Participants in Group B receive an ephedrine infusion at 1.25 mg/min, while those in Group C receive a higher dosage of 1.5 mg/min. This design allows for direct comparison of the two dosages of ephedrine against the control, enabling evaluation of their effectiveness in preventing maternal hypotension following spinal anesthesia during cesarean sections.

DRUG

Ephedrine

The interventions in this study include a control group receiving normal saline, which serves as an inert placebo to assess the effectiveness of the active treatments. Participants in Group B receive an ephedrine infusion at 1.25 mg/min, while those in Group C receive a higher dosage of 1.5 mg/min. This design allows for direct comparison of the two dosages of ephedrine against the control, enabling evaluation of their effectiveness in preventing maternal hypotension following spinal anesthesia during cesarean sections.

Trial Locations (1)

Unknown

B.P. koirala Institute of Health Sciences, Dharān

All Listed Sponsors
lead

B.P. Koirala Institute of Health Sciences

OTHER

NCT06668337 - Ephedrine Doses to Prevent Maternal Hypotension After Spinal Anesthesia in Cesarean Section | Biotech Hunter | Biotech Hunter