The Intensive Care Platform Trial

PHASE4RecruitingINTERVENTIONAL
Enrollment

10,000

Participants

Timeline

Start Date

June 26, 2025

Primary Completion Date

December 31, 2035

Study Completion Date

December 31, 2035

Conditions
Intensive Care PatientsIntensive Care Unit PatientsCritical Illness
Interventions
DRUG

Albumin

Albumin should be used for the following indications: 1. During circulatory failure in addition to crystalloids (resuscitation). 2. For substitution in case of: suspected or overt albumin loss OR P-albumin levels below or equal to 25 g/L. Decisions around timing, volume, and concentration of albumin, and its use for other indications, are at the clinician's discretion. P-albumin should be measured according to local practice.

OTHER

No albumin use

Albumin should not be used. In case of the following special circumstances, albumin may be considered: 1. Large ascites drainage (i.e., equal to or more than 1 L tapped) 2. Spontaneous bacterial peritonitis 3. Hepatorenal syndrome.

Trial Locations (19)

2100

NOT_YET_RECRUITING

Department of Cardiothoracic Anaesthesia and Intensive care, Copenhagen Universisty Hospital - Rigshospitalet, Copenhagen

RECRUITING

Department of Intensive Care, Copenhagen University Hospital - Rigshospitalet, Copenhagen

NOT_YET_RECRUITING

Neuroanaesthesiology, Copenhagen University Hospital - Rigshospitalet, Copenhagen

2400

NOT_YET_RECRUITING

Department of anesthesiology and intensive care, Bispebjerg-Frederiksberg Hospital, Copenhagen

2650

NOT_YET_RECRUITING

Anaesthesiology and Intensive Care, Amager and Hvidovre Hospital, Hvidovre

2730

NOT_YET_RECRUITING

Department of Anesthesiology and Intensive Care, Copenhagen University Hospital Herlev, Herlev

3400

NOT_YET_RECRUITING

Department of Anaesthesia and Intensive Care Medicine, Copenhagen University Hospital - North Zealand, Hillerød

4200

NOT_YET_RECRUITING

Insive care, Slagelse Hospital, Slagelse

4600

RECRUITING

Department of Anesthesia, Zealand University Hospital, Køge

4800

NOT_YET_RECRUITING

Anesthesiology (ICU), Zealand University Hospital, Nykøbing Falster, Nykøbing Falster

5000

RECRUITING

Department of Anesthesiology and Intensive Care, Odense University Hospital, Odense

6000

RECRUITING

Department of Anesthesia and intensive care medicine, Kolding Hospital, Kolding

6200

NOT_YET_RECRUITING

Anaesthesia, Hospital Sønderjylland, Aabenraa

7400

NOT_YET_RECRUITING

Department of Anaesthesiology and Intensive Care, Gødstrup Hospital, Herning

8200

NOT_YET_RECRUITING

Department of Intensive Care Nord , Aarhus University Hospital, Aarhus

NOT_YET_RECRUITING

Department of Intensive Care Øst, Aarhus University Hospital, Aarhus

8800

NOT_YET_RECRUITING

Department of Anaesthesiology and Intensive Care, Regional Hospital Viborg, Viborg

8930

NOT_YET_RECRUITING

Operation og Intensiv, Regional Hospital Randers, Randers

9000

RECRUITING

Department of Anaesthesia and Intensive Care, Aalborg University Hospital, Aalborg

All Listed Sponsors
collaborator

Rigshospitalet, Denmark

OTHER

collaborator

Bispebjerg Hospital

OTHER

collaborator

Herlev Hospital

OTHER

collaborator

Hillerod Hospital, Denmark

OTHER

collaborator

Kolding Sygehus

OTHER

collaborator

Zealand University Hospital

OTHER

collaborator

Slagelse Hospital

OTHER

collaborator

Viborg Regional Hospital

OTHER

collaborator

Aalborg University Hospital

OTHER

collaborator

Aarhus University Hospital

OTHER

collaborator

Gødstrup Hospital

OTHER

collaborator

Copenhagen University Hospital, Hvidovre

OTHER

collaborator

Odense University Hospital

OTHER

collaborator

Randers Regional Hospital

OTHER

collaborator

Section of Biostatistics University of Copenhagen, Copenhagen

UNKNOWN

collaborator

North Denmark Region

OTHER_GOV

collaborator

Region Capital Denmark

OTHER

collaborator

Region Zealand

OTHER

collaborator

University Medical Center Groningen

OTHER

collaborator

Steno Diabetes Center Copenhagen

OTHER

collaborator

Karolinska Institutet

OTHER

collaborator

Oslo University Hospital

OTHER

collaborator

University Hospital, Basel, Switzerland

OTHER

collaborator

Tampere University

OTHER

collaborator

Collaboration of Research in Intensive Care

UNKNOWN

collaborator

Danish Intensive Care Database

UNKNOWN

collaborator

The National University Hospital of Iceland

UNKNOWN

lead

Anders Perner

OTHER