Evaluating Modulation Effects of Burst Stimulation Patterns Using SEEG

Investigators use single-pulse electrical stimulations at 1Hz to elicit cortico-cortical evoked potentials

The repetitive delivery of pairs of stimulation pulses is DES patten with a 5-50 ms interval between each pulse, constitutes repetitive paired-pulse stimulation.

Stepwise incremental stimulation ranging from 5 Hz to 145 Hz following a cyclic pattern.

Burst stimulation pattern consisting of short bursts delivered once a second and an intraburst frequency of 50 Hz, 100 Hz, 150 Hz, 175 Hz and 200 Hz