Comparison of High Flow Vs Standard Nasal Cannula in Children with Burns Under Sedoanalgesia

NACompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

March 10, 2022

Primary Completion Date

August 30, 2022

Study Completion Date

October 1, 2022

Conditions
Burns
Interventions
OTHER

Conventional Nasal Cannula

The initial flow rate for nasal cannula oxygen was set at 3 L/min. In cases of hypoxia, the oxygen concentration was adjusted by increasing the flow rate by 1 to 2 L/min.

OTHER

High-flow nasal cannula

The high-flow nasal oxygenation device was set to a temperature of 36°C and an FiO2 of 0.4. The initial oxygen flow rate for the high flow group was determined according to the age and weight of the patients, based on our pediatric intensive care team's guidelines and the reference from the Slain study. When SpO2 fell below 94%, it was considered hypoxia, and the flow rate was increased by 2 to 4 L/min.

DRUG

midazolam, ketamine, propofol

Sedation was done with IV midazolam 0.025 to 0.1 mg/kg, IV ketamine 0.25 to 0.5 mg/kg, and IV propofol (1%) 0.25 to 0.5 mg/kg

DRUG

Propofol

Sedation maintenance was done by propofol 0.5 to 1 mg/kg/h

Trial Locations (1)

34764

Umraniye Education and Research hospital, Istanbul

All Listed Sponsors
lead

Zeliha Tuncel

OTHER_GOV