Mechanism of Nitric Oxide on Ventilator-induced Diaphragm Dysfunction with Extracorporeal Membrane Lung Assistance

Active, not recruitingOBSERVATIONAL
Enrollment

80

Participants

Timeline

Start Date

January 16, 2024

Primary Completion Date

September 30, 2025

Study Completion Date

December 30, 2025

Conditions
Tracheal IntubationExtracorporeal Membrane OxygenationNitric OxideVentilator-induced Diaphragmatic Dysfunction
Interventions
DRUG

Nitric Oxide

Depending on the indication, the subjects will be given NO treatment or not. In ECMO assisted mechanical ventilation + NO treatment group, the subjects will be randomly assigned to NO treatment via ventilator or membrane oxygenator.

Trial Locations (1)

430071

Zhongnan Hospital of Wuhan University, Wuhan

All Listed Sponsors
lead

Zhongnan Hospital

OTHER

NCT06660784 - Mechanism of Nitric Oxide on Ventilator-induced Diaphragm Dysfunction with Extracorporeal Membrane Lung Assistance | Biotech Hunter | Biotech Hunter