A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS)

PHASE3RecruitingINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

September 25, 2024

Primary Completion Date

August 21, 2026

Study Completion Date

October 2, 2026

Conditions
Dravet Syndrome
Interventions
DRUG

LP352

LP352 will be administered orally or through G-tube/ percutaneous endoscopic gastrostomy (PEG) tube

DRUG

Placebo

Participants will be administered with matching placebo orally or through G-tube/ PEG tube

Trial Locations (63)

2031

RECRUITING

Prince of Wales Hospital, Randwick

RECRUITING

Sydney Children's Hospital, Randwick

2650

RECRUITING

UZ Antwerpen, Antwerp

3084

RECRUITING

Austin Hospital, Heidelberg

4029

RECRUITING

Royal Brisbane & Women's Hospital, Herston

4101

RECRUITING

Queensland Children's Hospital, South Brisbane

8041

RECRUITING

Hospital de La Santa Creu i Sant Pau, Barcelona

11000

RECRUITING

University Clinical Center of Serbia - Dr Subotica 6 - PPDS, Belgrade

RECRUITING

Clinic for Neurology and Psychiatry for Children and Youth, Belgrade

RECRUITING

Mother and Child Health Care Institute of Serbia Dr Vukan Cupic, Belgrade

13386

RECRUITING

AP-HM- Hôpital de La Timone, Marseille

16147

RECRUITING

Istituto G Gaslini Ospedale Pediatrico IRCCS - INCIPIT - PIN, Genova

24105

RECRUITING

Universitätsklinikum Schleswig-Holstein - Campus Kiel, Kiel

27100

RECRUITING

Fondazione Istituto Neurologico Nazionale Casimiro Mondino IRCCS, Pavia

28010

RECRUITING

Hospital Universitario Vithas Madrid La Milagrosa, Madrid

28034

RECRUITING

Hospital Ruber Internacional (Grupo Quironsalud), Madrid

29010

RECRUITING

Hospital Regional Universitario de Malaga - Hospital General, Málaga

29016

RECRUITING

Hospital Vithas Malaga, Málaga

30329

COMPLETED

Rare Disease Research, LLC - Atlanta - RDR - PIN, Atlanta

31008

RECRUITING

Hospital Universitario de Navarra, Pamplona

31330

RECRUITING

Centre Hospitalier Universitaire de Toulouse, Toulouse

33617

RECRUITING

Gesellschaft für Epilepsieforschung e.V., Bielefeld

34000

RECRUITING

University Clinical Center Kragujevac, Kragujevac

35203

RECRUITING

CHU de Rennes - Hôpital Pontchaillou, Rennes

37126

RECRUITING

Azienda Ospedaliera Universitaria Integrata Di Verona, Verona

50139

RECRUITING

Azienda Ospedaliero Universitaria A Meyer - INCIPIT - PIN, Florence

59000

RECRUITING

Hôpital Roger Salengro, Lille

60528

RECRUITING

Klinikum der Johann-Wolfgang Goethe-Universitat, Frankfurt am Main

67098

RECRUITING

CHU de Strasbourg - Hôpital de Hautepierre, Strasbourg

69500

RECRUITING

Hospices Civils de Lyon - Hôpital Pierre Wertheimer, Bron

75019

RECRUITING

AP-HP - Hôpital universitaire Robert-Debré, Paris

77030

RECRUITING

The University of Texas Medical School at Houston, Houston

78757

RECRUITING

Child Neurology Consultants of Austin, Austin

88214

RECRUITING

Epilepsie-Zentrum Bodensee, Ravensburg

98405

RECRUITING

Multicare Health System - Mary Bridge Pediatrics, Tacoma

102627

RECRUITING

Peking University First Hospital - Daxing Campus, Beijing

510260

RECRUITING

The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou

72202-3500

RECRUITING

Arkansas Children's Hospital - PIN, Little Rock

90095-8346

RECRUITING

David Geffen School of Medicine at UCLA, Los Angeles

94304-1510

RECRUITING

The Stanford Division of Child Neurology, Palo Alto

94143-2350

RECRUITING

UCSF Children's Hospital, San Francisco

80045-7106

RECRUITING

Children's Hospital Colorado., Aurora

32561-4458

RECRUITING

NW FL Clinical Research Group, LLC, Gulf Breeze

33155-3009

RECRUITING

Nicklaus Children's Hospital - PIN, Miami

32806-5411

RECRUITING

Research Institute of Orlando LLC, Orlando

33609-4190

RECRUITING

Pediatric Epilepsy and Neurology Specialists, Tampa

20817-1844

RECRUITING

Mid-Atlantic Epilepsy and Sleep Center, Bethesda

55905-0001

RECRUITING

Mayo Clinic - PIN, Rochester

07039-5817

RECRUITING

Institute of Neurology and Neurosurgery at Saint Barnabas, LLC, Livingston

07960

RECRUITING

Northeast Regional Epilepsy Group - Morristown - 310 Madison Ave, Morristown

97239-3011

RECRUITING

Oregon Health and Science University, Portland

38103-2816

RECRUITING

Le Bonheur Childrens Hospital, Memphis

76104-2710

RECRUITING

Cook Children's Medical Center - Jane and John Justin Neurosciences Center, Fort Worth

05403-010

RECRUITING

Instituto de Psiquiatria HC FMUSP, São Paulo

N6A 5W9

RECRUITING

London Health Sciences Centre -800 Commissioners Rd E, London

00168

RECRUITING

Fondazione Policlinico Universitario A Gemelli - Rome - PPDS, Rome

LV-1004

RECRUITING

Children's Clinical University Hospital, Riga

3000-602

RECRUITING

ULS de Coimbra, EPE - Hospital Pediátrico de Coimbra, Coimbra

4050-651

RECRUITING

ULS de Santo António, EPE - Centro Materno Infantil Norte, Porto

08950

RECRUITING

Hospital Sant Joan de Deu - PIN, Espluges de Llobregat

08035

RECRUITING

Hospital Universitario Vall d'Hebron - PPDS, Barcelona

NE1 4LP

RECRUITING

Royal Victoria Infirmary, Newcastle upon Tyne

G51 4TF

RECRUITING

Queen Elizabeth University Hospital - PPDS, Glasgow

Sponsors
All Listed Sponsors
lead

Longboard Pharmaceuticals

INDUSTRY