Efficacy of Collagen, Propolis Plus Quercetin (Proqutin®), Bacillus Coagulans, Hyaluronic Acid and Chondroitin Sulphate and D-Mannose to Avoid Symptoms and Prevents Recurrence in Women With Recurrent Urinary Tract Infections

PHASE4CompletedINTERVENTIONAL
Enrollment

148

Participants

Timeline

Start Date

February 1, 2023

Primary Completion Date

February 10, 2024

Study Completion Date

September 30, 2024

Conditions
Urinary Tract Infection (Diagnosis)
Interventions
DRUG

Fosfomycin 3 g

Fosfomycin trometamol 3 g administered orally in a single dose every ten days for three months, repeated every three months for a total treatment duration of 12 months.

DIETARY_SUPPLEMENT

Uroxin 4G

Dietary supplement of D-mannose, collagen, hyaluronic acid, chondroitin sulphate, propolis plus quercetin (Proqutin ®) and Bacillus Coagulans (Uroxin 4G, Pharmasuisse laboratories, Milan, Italy) administered twice daily for seven days in the first month, then once daily for 14 days a month for two months, repeated every three months for a total treatment duration of 12 months.

DRUG

Combination of dietary supplement and fosfomycin

Fosfomycin trometamol 3 g administered orally in a single dose every ten days for three months, repeated every three months for a total treatment duration of 12 months, combined with an oral formulation of D-mannose, collagen, hyaluronic acid, chondroitin sulphate, propolis plus quercetin (Proqutin ®) and Bacillus Coagulans (Uroxin 4G, Pharmasuisse laboratories, Milan, Italy) administered twice daily for seven days in the first month, then once daily for 14 days a month for two months, repeated every three months for a total treatment duration of 12 months.

Trial Locations (1)

80138

University of Campania Luigi Vanvitelli, Napoli

All Listed Sponsors
collaborator

pharmaSuisse

UNKNOWN

lead

University of Campania Luigi Vanvitelli

OTHER