Treating Loneliness In The Older Adult With Depression With tDCS

NARecruitingINTERVENTIONAL
Enrollment

180

Participants

Timeline

Start Date

October 29, 2024

Primary Completion Date

October 20, 2026

Study Completion Date

December 30, 2026

Conditions
Major Depressive DisorderLoneliness
Interventions
DEVICE

Transcranial direct current stimulation (tDCS) on the Left DLPFC

The tDCS parameters were set to a current of 2mA for a single session lasting 20 minutes. For stimulating the lDLPFC, the positive electrode was placed at position F3, and the negative electrode was placed in the right supraorbital area/FP2 (e.g., Dubreuil-Vall et al., 2021, Biol Psychiatry: CNNI).

DEVICE

Transcranial direct current stimulation (tDCS) on the right VLPFC

The tDCS parameters were set to a current of 2mA for a single session lasting 20 minutes. Based on the EEG 10-20 international system, the positive electrode for stimulating the rVLPFC was placed at position F6, while the negative electrode was placed in the left supraorbital area/FP1 (e.g., He et al., 2020, Psychol Med)

DEVICE

Sham stimulation group

The electrode positions were randomized to match those of the rVLPFC or lDLPFC groups, but the stimulation only lasted for the first 30 seconds.

Trial Locations (1)

510370

RECRUITING

Guangzhou Brain Hospital, Guangzhou

All Listed Sponsors
collaborator

The University of Hong Kong

OTHER

lead

Guangzhou Psychiatric Hospital

OTHER_GOV