Effect of Adding Glycerol to Electrolyte Beverages on Fluid Balance in Healthy Euhydrated Men and Women at Rest

NARecruitingINTERVENTIONAL
Enrollment

95

Participants

Timeline

Start Date

September 30, 2024

Primary Completion Date

May 30, 2025

Study Completion Date

May 30, 2025

Conditions
Fluid Balance
Interventions
OTHER

Placebo beverage, kiwi-strawberry flavor (Part 1 and Part 2)

9.3 oz (276 ml) aliquots 3 times for a total of 28 oz (828 ml) over a 35 min period followed by 25 min rest until Time 0 post-dose.

OTHER

0% carbohydrate electrolyte solution with glycerol beverage (Part 1 only)

9.3 oz (276 ml) aliquots 3 times for a total of 28 oz (828 ml) over a 35 min period followed by 25 min rest until Time 0 post-dose. Beverage matched to placebo for color and flavor.

OTHER

0% carbohydrate electrolyte solution without glycerol beverage (Part 1 only)

9.3 oz (276 ml) aliquots 3 times for a total of 28 oz (828 ml) over a 35 min period followed by 25 min rest until Time 0 post-dose. Beverage matched to placebo for color and flavor.

OTHER

1% carbohydrate electrolyte solution with glycerol beverage (Parts 1 and 2)

9.3 oz (276 ml) aliquots 3 times for a total of 28 oz (828 ml) over a 35 min period followed by 25 min rest until Time 0 post-dose. Beverage matched to placebo for color and flavor.

OTHER

6% carbohydrate electrolyte solution with glycerol beverage (Parts 1 and 2)

9.3 oz (276 ml) aliquots 3 times for a total of 28 oz (828 ml) over a 35 min period followed by 25 min rest until Time 0 post-dose. Beverage matched to placebo for color and flavor.

OTHER

6% carbohydrate electrolyte solution without glycerol beverage (Part 2 only)

9.3 oz (276 ml) aliquots 3 times for a total of 28 oz (828 ml) over a 35 min period followed by 25 min rest until Time 0 post-dose. Beverage matched to placebo for color and flavor.

OTHER

2% carbohydrate electrolyte solution without glycerol beverage (Part 2 only)

9.3 oz (276 ml) aliquots 3 times for a total of 28 oz (828 ml) over a 35 min period followed by 25 min rest until Time 0 post-dose. Beverage matched to placebo for color and flavor.

Trial Locations (1)

10595

RECRUITING

PepsiCo R&D, Gatorade Sports Science Institute, Valhalla

All Listed Sponsors
lead

PepsiCo Global R&D

INDUSTRY