Thrombectomy Versus Best Medical Management in Large Vessel Occlusion Stroke Patients Presenting Beyond 24 Hours and With Presence of Collateral Flow on CT Angiography

NARecruitingINTERVENTIONAL
Enrollment

350

Participants

Timeline

Start Date

June 25, 2024

Primary Completion Date

December 31, 2027

Study Completion Date

December 31, 2027

Conditions
Stroke AcuteThrombectomyMedical TreatmentLarge Vessel Occlusion
Interventions
PROCEDURE

Endovascular Thrombectomy

"Endovascular thrombectomy (EVT) in this clinical trial involves the mechanical removal of a thrombus from a blocked large cerebral artery using specialized devices like stent retrievers or aspiration catheters. Key distinguishing features of this EVT protocol include:~* Extended Time Window: Unlike standard EVT, which is typically performed within 24 hours after symptom onset, this intervention targets patients presenting beyond 24 hours.~* Collateral Circulation Assessment: Multi-phase CT angiography (CTA) is employed to evaluate collateral flow, prioritizing patients with favorable collateral grades. This selection process helps ensure the identification of patients most likely to benefit from EVT despite the late presentation."

Trial Locations (1)

300070

RECRUITING

Tianjin Huanhu Hospital, Tianjin

All Listed Sponsors
lead

Tianjin Huanhu Hospital

OTHER