A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

PHASE2/PHASE3RecruitingINTERVENTIONAL
Enrollment

280

Participants

Timeline

Start Date

November 22, 2024

Primary Completion Date

March 31, 2034

Study Completion Date

August 31, 2034

Conditions
Alzheimers DiseaseDementiaAlzheimers Disease, Familial
Interventions
DRUG

Remternetug

Administered subcutaneously every 12 weeks

DRUG

Matching Placebo (Remternetug)

Administered as subcutaneous injection of placebo every 12 weeks

Trial Locations (35)

2031

NOT_YET_RECRUITING

Neuroscience Research Australia, Randwick

3010

NOT_YET_RECRUITING

Mental Health Research Institute, Melbourne

8011

NOT_YET_RECRUITING

New Zealand Brain Research Institute, Christchurch

8036

NOT_YET_RECRUITING

Hospital Clínic I Provincial de Barcelona, Barcelona

10016

RECRUITING

New York University Medical Center, New York

14269

NOT_YET_RECRUITING

Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez, Mexico City

15213

RECRUITING

University of Pittsburgh, Pittsburgh

25125

NOT_YET_RECRUITING

IRCCS Centro San Giovanni di Dio Fatebenefratelli, Brescia

30329

NOT_YET_RECRUITING

Emory University, Atlanta

31059

NOT_YET_RECRUITING

CHU de Toulouse - Hôpital Purpan, Toulouse

35294

RECRUITING

University of Alabama in Birmingham, Birmingham

46202

RECRUITING

Indiana University School of Medicine, Indianapolis

50134

NOT_YET_RECRUITING

Azienda Ospedaliera Universitaria Careggi, Florence

59037

NOT_YET_RECRUITING

Hopital Roger Salengro - CHU Lille, Lille

60068

RECRUITING

Advocate Lutheran General Hospital, Park Ridge

63110

RECRUITING

Washington University in St. Louis, St Louis

69677

NOT_YET_RECRUITING

Groupe Hospitalier Pitie-Salpetriere, Paris

NOT_YET_RECRUITING

Hopital Neurologique Pierre Wertheimer, Bron

72076

NOT_YET_RECRUITING

Universitaetsklinikum Tubingen, Tübingen

75231

RECRUITING

Kerwin Research and Memory Center, Dallas

76031

NOT_YET_RECRUITING

CHU de Rouen - Hôpital Charles Nicolle, Rouen

81377

NOT_YET_RECRUITING

LMU-Campus Grosshadern, Munich

92037

RECRUITING

University of California San Diego Medical Center, La Jolla

98195

RECRUITING

University of Washington, Seattle

06510

RECRUITING

Yale University School of Medicine, New Haven

02096

RECRUITING

Butler Hospital, Providence

C1428AQK

NOT_YET_RECRUITING

Instituto de Investigaciones Neurologicas Raul Carrea, FLENI, Ciudad Autonoma de Buenos Aire

V6T 2B5

NOT_YET_RECRUITING

UBC Hospital, Vancouver

M4N 3M5

RECRUITING

Sunnybrook Health Sciences Centre, Toronto

H4H 1R3

NOT_YET_RECRUITING

McGill Center for Studies in Aging, Verdun

G1J 1Z4

NOT_YET_RECRUITING

CHU de Quebec - Hôpital de l' Enfant Jésus, Québec

Unknown

NOT_YET_RECRUITING

Grupo de Neurociencias Sede de la Universidad de Antioquia, Medellín

1081 GM

NOT_YET_RECRUITING

Brain Research Center, Amsterdam

00936

NOT_YET_RECRUITING

University of Puerto Rico, School of Medicine, San Juan

WC1B 3BG

NOT_YET_RECRUITING

The National Hospital for Neurology and Neurosurgery, London

All Listed Sponsors
collaborator

Alzheimer's Association

OTHER

collaborator

Eli Lilly and Company

INDUSTRY

collaborator

National Institute on Aging (NIA)

NIH

collaborator

GHR Foundation

UNKNOWN

collaborator

Private Donors

UNKNOWN

lead

Washington University School of Medicine

OTHER