90
Participants
Start Date
October 31, 2024
Primary Completion Date
May 31, 2025
Study Completion Date
May 31, 2025
Strict adherence to European guidelines
"The goal is to maintain a neutral fluid balance throughout the course of intubation if clinical practice allows. Therefore:~* From the start of mechanical ventilation, the maximum maintenance fluids is 65% of the maintenance fluids proposed by the Holliday \& Segar formula. Fluid resuscitation in the first hours after intubation is at the discretion of the attending physician.~* Any other interventions to maintain a neutral fluid balance (e.g., starting diuretics, reducing fluid boluses, decreasing creep fluids, or using more concentrated enteral feeding) are at the discretion of the attending physician.~* Throughout the intervention, the attending physician decides if clinical practice allows for a decrease in fluid balance, and international feeding goals must always be met."
Radboudumc, Nijmegen
Amsterdam MC, Amsterdam
ErasmusMC, Rotterdam
Radboud University Medical Center
OTHER