The Efficient PICU Fluid Care Evaluation

NANot yet recruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

October 31, 2024

Primary Completion Date

May 31, 2025

Study Completion Date

May 31, 2025

Conditions
Respiratory Insufficiency Requiring Mechanical VentilationFluid OverloadFluid Balance
Interventions
OTHER

Strict adherence to European guidelines

"The goal is to maintain a neutral fluid balance throughout the course of intubation if clinical practice allows. Therefore:~* From the start of mechanical ventilation, the maximum maintenance fluids is 65% of the maintenance fluids proposed by the Holliday \& Segar formula. Fluid resuscitation in the first hours after intubation is at the discretion of the attending physician.~* Any other interventions to maintain a neutral fluid balance (e.g., starting diuretics, reducing fluid boluses, decreasing creep fluids, or using more concentrated enteral feeding) are at the discretion of the attending physician.~* Throughout the intervention, the attending physician decides if clinical practice allows for a decrease in fluid balance, and international feeding goals must always be met."

Trial Locations (3)

6525 GA

Radboudumc, Nijmegen

1100 DD

Amsterdam MC, Amsterdam

3015 CN

ErasmusMC, Rotterdam

All Listed Sponsors
lead

Radboud University Medical Center

OTHER