Intrapartum Glucose Control and Risk of Neonatal Hypoglycemia

NARecruitingINTERVENTIONAL
Enrollment

218

Participants

Timeline

Start Date

December 3, 2024

Primary Completion Date

December 31, 2025

Study Completion Date

June 30, 2026

Conditions
Gestational Diabetes Mellitus in PregnancyPregestational Diabetes MellitusNeonatal Hypoglycemia
Interventions
OTHER

Standard Intrapartum Glucose Target Range

Intrapartum maternal glucose management involves frequent blood sugar checks and the use of insulin intravenous drip as needed. Maternal capillary blood sugar is checked every 4 hours in early labor, 2 hours in active labor and hourly during the second stage of labor. The frequency of maternal glucose monitoring will not differ by study group. The goal intrapartum glucose target range will be 70-110mg/dl. Insulin infusion will be initiated when maternal capillary glucose exceeds 110 mg/dL. Once an insulin infusion is initiated, glucose monitoring frequency will occur by protocol. A hypoglycemia protocol is initiated if the maternal blood sugar is less than 60mg/dl.

OTHER

Liberalized Intrapartum Glucose Target Range

Intrapartum maternal glucose management involves frequent blood sugar checks and the use of insulin intravenous drip as needed. Maternal capillary blood sugar is checked every 4 hours in early labor, 2 hours in active labor and hourly during the second stage of labor. The frequency of maternal glucose monitoring will not differ by study group. The goal intrapartum glucose target range will be 70-160mg/dl. Insulin infusion will be initiated when maternal capillary glucose exceeds 160 mg/dL. Once an insulin infusion is initiated, glucose monitoring frequency will occur by protocol. A hypoglycemia protocol is initiated if the maternal blood sugar is less than 60mg/dl.

Trial Locations (1)

15213

RECRUITING

Magee-Women's Hospital of UPMC, Pittsburgh

All Listed Sponsors
lead

University of Pittsburgh

OTHER