Effect of Vitamin D Supplementation on the Efficacy and Adverse Effects of Neoadjuvant Therapy in Patients with Breast Cancer

NARecruitingINTERVENTIONAL
Enrollment

140

Participants

Timeline

Start Date

October 18, 2024

Primary Completion Date

January 31, 2026

Study Completion Date

April 30, 2026

Conditions
Vitamin DNeoadjuvant TherapyBreast CancerAdverse ReactionEfficacyChemotherapy
Interventions
DRUG

Neoadjuvant therapy + vitamin D2

Before the start of treatment and every 3 weeks thereafter, participants will receive injections of vitamin D2 at a dosage of 10 mg until the completion of neoadjuvant therapy. They will undergo the standard neoadjuvant regimen, which includes the 10 mg injection of vitamin D2 per cycle during the therapy. The dosage of neoadjuvant drugs may be tailored based on the physician's clinical judgment.

DRUG

Neoadjuvant therapy

Participants will receive the standard neoadjuvant regimen during each cycle of neoadjuvant therapy. The dosage of the neoadjuvant drugs may be tailored based on the physician's clinical judgment.

Trial Locations (2)

810000

NOT_YET_RECRUITING

Qinghai University Affiliated Hospital, Xining

RECRUITING

Qinghai University Affiliated Hospital, Xining

All Listed Sponsors
lead

Jiuda Zhao

OTHER