Preoperative Partial Breast Reirradiation and Repeat Breast-conserving Surgery in Patients With Recurrent Breast Cancer: the REPEAT Trial

PHASE2RecruitingINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

January 1, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Recurrent Breast CarcinomaIpsilateral Recurrence
Interventions
RADIATION

ablative single-dose PBI

ablative single-dose PBI followed by BCS after three weeks At baseline (prior to RT) and prior to BCS, toxicity, PROMS and cosmetic outcome will be assessed. Additionally, a preoperative MRI will be performed three weeks following RT to evaluate the acute tumor response.

Trial Locations (1)

Unknown

RECRUITING

Amsterdam UMC / VU Medical Centre, Amsterdam

All Listed Sponsors
lead

Amsterdam UMC, location VUmc

OTHER