We-INtervention Among Chinese HIV-serodiscordant Male Couples

NANot yet recruitingINTERVENTIONAL
Enrollment

320

Participants

Timeline

Start Date

September 1, 2025

Primary Completion Date

April 30, 2027

Study Completion Date

June 30, 2027

Conditions
HIV
Interventions
BEHAVIORAL

We-INtervention

The We-INtervention focuses on the relationship dynamics of HIV-serodiscordant male couples. In developing the intervention, we reviewed relevant theories and frameworks, such as the cognitive transactional model, the systemic transactional model, the dyadic illness management model, and the intersectional framework of stigma. The three weekly 60-minute sessions are Session 1: We-disease appraisal. Despite stigma related to their dual minority identities, couples develop a perception of HIV as a shared disease, enhancing illness control. Session 2: Couple communication. Couples undertake skill-building exercises on effective communication techniques to strengthen their relationship. Session 3: Dyadic coping. Couples learn to optimize preference and value assessments in HIV management. A few skill-building exercises help them mobilize and maintain mutual support and develop joint problem-solving skills.

BEHAVIORAL

Usual Care Group

The participants in the control condition will receive health information pamphlets. The HIV-seropositive partners will receive information on HIV-related knowledge (e.g., symptoms, comorbidity, stages, and opportunistic infection), treatment (e.g., ART and side effects), and management (e.g., nutrition and mental health). The HIV-seronegative partner will receive information on HIV transmission (e.g., risk factors), prevention (e.g., safe sex and PrEP), and testing.

Trial Locations (4)

Unknown

Fangzhouai Garden, Xiamen

Guangzhou Yuele Healthcare Service Center, Guangzhou

Community Always There, Shenzhen

Jin Tang Six-Color Rainbow Healthcare Center, Chengdu

All Listed Sponsors
lead

City University of Hong Kong

OTHER

NCT06639932 - We-INtervention Among Chinese HIV-serodiscordant Male Couples | Biotech Hunter | Biotech Hunter