Flexibility, Alcohol Misuse, and Excitation

NARecruitingINTERVENTIONAL
Enrollment

66

Participants

Timeline

Start Date

July 18, 2024

Primary Completion Date

September 30, 2027

Study Completion Date

November 30, 2027

Conditions
Behavioral FlexibilityHealthy VolunteersHigh Risk Alcohol Use
Interventions
DEVICE

10 Hz transcranial alternating current stimulation (tACS)

10 Hz bi-frontal tACS: Alternating current stimulation is delivered by an XCSITE 100 device (Pulvinar Neuro, Chapel Hill, NC), through three conductive carbon-rubber electrodes. Electrodes are placed over the apex of the head (Cz) and the prefrontal cortex bilaterally (F3 and F4). Stimulation is delivered during the second half of the HABIT Test session. Stimulation parameters: 2mA peak-to-peak 10Hz sine-wave flanked by 10 second linear envelope ramps in and out for a total duration of 30 min and 20 seconds.

DEVICE

sham transcranial alternating current stimulation (tACS)

Sham tACS: The procedure for sham stimulation will be identical, but it will last for 2 minutes instead of 30 minutes.

Trial Locations (1)

27599

RECRUITING

University of North Carolina, Chapel Hill, Chapel Hill

All Listed Sponsors
collaborator

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NIH

lead

University of North Carolina, Chapel Hill

OTHER