Brain Signal Training to Enhance Affect Down-regulation

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

164

Participants

Timeline

Start Date

April 23, 2025

Primary Completion Date

November 30, 2026

Study Completion Date

August 31, 2027

Conditions
Borderline Personality Disorder
Interventions
BIOLOGICAL

Amygdala neurofeedback

Real-time fMRI neurofeedback from amygdala's blood oxygenation level dependent (BOLD) signal + negative emotional picture viewing. Instruction to regulate feedback via down-regulation of one's emotional response.

BEHAVIORAL

Sham neurofeedback

Recorded neurofeedback from a different participant + negative emotional picture viewing. Instruction to regulate feedback via down-regulation of one's emotional response.

Trial Locations (4)

35392

RECRUITING

University clinic Giessen, Giessen

68159

RECRUITING

Central Institute of Mental Health, Mannheim

72076

RECRUITING

University Clinic Tuebingen, Tübingen

79104

RECRUITING

University clinic Freiburg, Freiburg im Breisgau

All Listed Sponsors
collaborator

University Medical Center Freiburg

OTHER

collaborator

University of Giessen

OTHER

collaborator

University Hospital Tuebingen

OTHER

lead

Central Institute of Mental Health, Mannheim

OTHER