Predictive Modeling of Necrotizing Skin Infections in Snakebite Patients

CompletedOBSERVATIONAL
Enrollment

99

Participants

Timeline

Start Date

January 1, 2020

Primary Completion Date

April 1, 2024

Study Completion Date

April 30, 2024

Conditions
Necrotizing Skin InfectionsSnakebite Envenomation
Interventions
DRUG

Antivenom Serum

Intravenous administration of 6000 IU of antivenom serum was given to patients envenomed by pit vipers. This treatment was based on Chinese guidelines for the management of snakebites. Additionally, patients received supportive treatments, including antibiotics to prevent infection, antihistamines for allergic reactions, and magnesium sulfate for localized swelling and pain relief.

PROCEDURE

Wound Debridement

Patients who did not develop necrotizing skin infections received wound management, including multiple punctures using a three-edged needle for toxin drainage, along with standard wound care and debridement as necessary to prevent infection and promote healing.

Trial Locations (1)

524002

Affiliated Hospital of Guangdong Medical University, Zhanjiang

All Listed Sponsors
collaborator

Central People's Hospital of Zhanjiang

OTHER

collaborator

Affiliated Hospital of Guangdong Medical University

OTHER

lead

Guangzhou Institute of Respiratory Disease

OTHER

NCT06622343 - Predictive Modeling of Necrotizing Skin Infections in Snakebite Patients | Biotech Hunter | Biotech Hunter