Effect of Unilateral Erector Spinae Plane Block Versus Intrathecal Morphine on Early Mobilization After Hip Replacement

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

September 23, 2024

Primary Completion Date

June 23, 2025

Study Completion Date

July 23, 2025

Conditions
Pain, Postoperative
Interventions
PROCEDURE

erector spinae plane block

In the erector spinae plane block (group E), an ultrasound-guided block will be performed on the ipsilateral side of the surgery while the patient is in lateral position 3-5 cm from the midline (10). Moving cephalic from the sacrum, we will identify the L5, L4, and L3 transverse processes and erector spinae muscles posteriorly. A 21 G and 70mm length needle will be directed in-plane, and the needle tip will be positioned anterior to the erector spinae muscle at the corner of the transverse process. After the initial saline injection, dissection of the plane will be observed by injecting a total volume of 20 ml composed of 10 micrograms dexmedetomidine in 2ml of normal saline and 18 ml of bupivacaine 0.25%, which is far from the toxic dose (10). Correct placement is defined as the spread of local anesthetic cranially and caudally from the injection point, dissecting the plane between the transverse processes and erector spinae muscles.

DRUG

Morphine

patients will receive 5 ml of subcutaneous lidocaine 1% then 3.5 ml of bupivacaine 0.5% and 0.1 mg of morphine in 0.25 ml of normal saline intrathecal

Trial Locations (1)

11956

RECRUITING

Faculty of Medicine- Cairo University, Cairo

All Listed Sponsors
lead

Cairo University

OTHER