NCT06620991View on ClinicalTrials.gov

Pre-operative Phentolamine Vs Intraoperative Esmolol Efficacy for Hypotensive Anesthesia in Functional Endoscopic Sinus Surgery

NANot yet recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

October 10, 2024

Primary Completion Date

April 1, 2025

Study Completion Date

April 1, 2025

Conditions
PreoperativePhentolamineIntraoperativeEsmololHypotensive AnesthesiaFunctional Endoscopic Sinus Surgery
Interventions
DRUG

Phentolamine

A loading dose of 1-5 mg IV bolus over 1 minute is given followed by an IV infusion of a rate of 0.1-2 mg/min according to patient desired target mean arterial pressure (MAP) 50-60 mmHg over a volume of 10ml

DRUG

Esmolol

A loading dose of 1 mg/kg IV infused over 1 minute is given followed by an IV infusion of 0.15-0.3 mg/kg/min according to patient desired target mean arterial pressure (MAP) 50-60 mmHg over total volume of 10ml

Trial Locations (1)

11591

Ain Shams University, Cairo

All Listed Sponsors
lead

Ain Shams University

OTHER

NCT06620991 - Pre-operative Phentolamine Vs Intraoperative Esmolol Efficacy for Hypotensive Anesthesia in Functional Endoscopic Sinus Surgery | Biotech Hunter | Biotech Hunter