Effects of High-Flow Nasal Cannula on Exercise Outcomes in Lung Transplant Candidates: A Pilot Study

NACompletedINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

June 2, 2021

Primary Completion Date

March 31, 2023

Study Completion Date

July 24, 2024

Conditions
Pulmonary DiseasesOxygen TherapyHigh-flow Nasal CannulaExercise Tolerance
Interventions
OTHER

Performance Tests

Three functional tests were performed: the six-minute walk test, incremental lower limb test with arterial blood gas analysis, and lower limb endurance test with inspiratory capacity measurement. Each test was conducted on different days with different devices: HFNC and conventional oxygen therapy, totaling six test days. The inspired oxygen fraction (FiO2) was titrated to maintain normoxia between 90% to 96% and was kept constant for both interfaces.

OTHER

Functional Tests

Three functional tests were performed: the six-minute walk test, incremental lower limb test with arterial blood gas analysis, and lower limb endurance test with inspiratory capacity measurement. Each test was conducted on different days with different devices: HFNC and conventional oxygen therapy, totaling six test days. The inspired oxygen fraction (FiO2) was titrated to maintain normoxia between 90% to 96% and was kept constant for both interfaces.

Trial Locations (1)

05652-900

Albert Einstein Israelite Hospital, São Paulo

All Listed Sponsors
lead

Hospital Israelita Albert Einstein

OTHER