The Efficacy of Amino Acid Supplementation in Treating Environmental Enteric Dysfunction Among Children At Risk of Malnutrition

NANot yet recruitingINTERVENTIONAL
Enrollment

66

Participants

Timeline

Start Date

November 1, 2024

Primary Completion Date

August 1, 2026

Study Completion Date

December 1, 2026

Conditions
Amino Acid, Stunting, Environmental Enteric Dysfunction
Interventions
DIETARY_SUPPLEMENT

Corn soy bean blended flour porridge plus indispensable amino acid

"Protocol treatment will start within two weeks of enrollment to the study. Following the baseline study assessments, each participant will receive corn-soy bean blended flour porridge supplemented with IAAs (histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, and valine) dosed at 12g/d and providing 1.5 times the estimated average requirement (EAR) for a healthy child (Intervention group). The porridge will provide 30% daily energy requirement. The study foods will be taken once daily by the child with at least three observed feeding sessions per week over the 4 weeks of the study to assess compliance.~Children in the control arm will receive corn-soy blended flour porridge without added amino acids."

Trial Locations (1)

Unknown

Kamuzu University of Health Sciences, Blantyre

All Listed Sponsors
collaborator

University of Glasgow

OTHER

lead

Kamuzu University of Health Sciences

OTHER

NCT06617130 - The Efficacy of Amino Acid Supplementation in Treating Environmental Enteric Dysfunction Among Children At Risk of Malnutrition | Biotech Hunter | Biotech Hunter