Dexmedetomidine Dosage for Postoperative Delirium and Cognitive Function in Elderly TKA Patients

NACompletedINTERVENTIONAL
Enrollment

132

Participants

Timeline

Start Date

July 1, 2024

Primary Completion Date

October 15, 2024

Study Completion Date

November 1, 2024

Conditions
Post Operative Delirium
Interventions
DRUG

Dexmedetomidine Injection [Precedex]

Dexmedetomidine (Precedex, 100 µg/ml) was provided as an intravenous (IV) loading dose of 1 µg/kg over 10-min

DRUG

Dexmedetomidine in 0.9 % NaCl 1,000 Mcg/250 mL (4 Mcg/mL) INTRAVEN INFUSION BOTTLE (ML)

Dexmedetomidine infusions were prepared to provide 0.5 µg/kg/h

DRUG

Dexmedetomidine in 0.9 % NaCl 1,000 Mcg/250 mL (4 Mcg/mL) INTRAVEN INFUSION BOTTLE (ML)

Dexmedetomidine infusions were prepared to provide 0.7 µg/kg/h

DRUG

Dexmedetomidine in 0.9 % NaCl 1,000 Mcg/250 mL (4 Mcg/mL) INTRAVEN INFUSION BOTTLE (ML)

Dexmedetomidine infusions were prepared to provide 1.1 µg/kg/h

DRUG

Normal saline

loading dose of saline was injected 10-min before induction of anesthesia.

Trial Locations (1)

13511

Tanta University, Tanta

All Listed Sponsors
lead

Tanta University

OTHER

NCT06614881 - Dexmedetomidine Dosage for Postoperative Delirium and Cognitive Function in Elderly TKA Patients | Biotech Hunter | Biotech Hunter