Precision Sensorimotor Neurorehabilitation Through Personalized Stimulation Loops

NARecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

May 16, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Parkinson Disease
Interventions
BEHAVIORAL

Hyper-personalized feedback (HPF intervention)

For lower limb motor rehabilitation, the investigator will employ real-time continuous feedback for movement aspects that are specific to each participant's motor deficit. The feedback will be adapted and tailored to each participant.

BEHAVIORAL

Targeted auditory stimulation during sleep (TASS verum intervention)

The investigator aim to reactivate rehabilitation- related memories through the presentation of auditory stimuli during sleep with the goal of promoting motor memory consolidation into stable motor commands

BEHAVIORAL

Control targeted auditory stimulation during sleep (TASS sham intervention)

Identical auditory presentation during the motor rehabilitation training, but not during the night (sham promotion memory reactivation)

Trial Locations (1)

8091

RECRUITING

University Hospital Zurich, Zurich

All Listed Sponsors
collaborator

ETH Zurich (Switzerland)

OTHER

collaborator

Cereneo AG

INDUSTRY

collaborator

University Children's Hospital, Zurich

OTHER

collaborator

Lake Lucerne Institute AG

UNKNOWN

lead

University of Zurich

OTHER