NCT06606886View on ClinicalTrials.gov

Effects of Hydroxyurea and Metformin in Transfusion Dependent Beta-Thalassemia

PHASE4RecruitingINTERVENTIONAL
Enrollment

96

Participants

Timeline

Start Date

September 16, 2024

Primary Completion Date

September 16, 2025

Study Completion Date

April 30, 2026

Conditions
Transfusion Dependent Beta-thalassemia
Interventions
DRUG

Tablet Metformin (Group A)

Tablet Metformin 500 mg/dose orally twice a day with meal for 1 year

DRUG

Tablet Hydroxyurea (Group B)

Tablet Hydroxyurea 10-20mg/kg once daily orally with breakfast for 1 year

Trial Locations (1)

Unknown

RECRUITING

Bahria University Health Sciences Campus, Karachi

All Listed Sponsors
lead

Bahria University

OTHER