Canadian Critical Care Comparative Effectiveness Platform

Vasopressor(s) will be titrated according to 56-60 range.

Vasopressor(s) will be titrated according to 61-65 range.

Vasopressor(s) will be titrated according to 66-70 range.

Vasopressor(s) will be titrated according to 71-75 range.

Once randomized, the participant will receive a platelet transfusion if their most recent platelet count is less than 10 x 109/L at the time of the planned procedure.

Once randomized, the participant will receive a platelet transfusion if their most recent platelet count is less than 20 x 109/L at the time of the planned procedure.

Once randomized, the participant will receive a platelet transfusion if their most recent platelet count is less than 30 x 109/L at the time of the planned procedure.

Once randomized, the participant will receive a platelet transfusion if their most recent platelet count is less than 40 x 109/L at the time of the planned procedure.

Once randomized, the participant will receive a platelet transfusion if their most recent platelet count is less than 50 x 109/L at the time of the planned procedure.