The EFFECTS of GAMBIR CATECHIN (UNCARIA GAMBIR ROXB) SUPPLEMENTATION on COGNITIVE FUNCTION, EXPRESSION of APP, MAPT, BDNF, IL-10, TGF-Β GENES, and PLASMA MDA LEVELS in the ELDERLY.

NACompletedINTERVENTIONAL
Enrollment

64

Participants

Timeline

Start Date

February 1, 2024

Primary Completion Date

August 6, 2024

Study Completion Date

August 15, 2024

Conditions
Elderly Individuals Aged 60 Years or OlderMild Cognitive Impairment (MCI)
Interventions
DIETARY_SUPPLEMENT

catechin extracts (health food)

"Type of intervention:~1. Purified gambir ≥ 90% (+)-Catechin~2. Dosage of 224 mg catechin capsule, once daily~3. Dosage of 224 mg placebo capsule, once daily~4. Cognitive function was assessed using MoCA-Ina and gene markers APP, MAPT, BDNF, IL-10, TGF-Beta and MDA Plasma.\""

OTHER

plasebo

Dosage of 224 mg placebo per capsule, once daily. Cognitive function was assessed using the MoCA-Ina and biomarkers including APP, MAPT, BDNF, IL-10, TGF-Beta, and plasma MDA.

Trial Locations (2)

25126

Andalas Univercity, Padang

25163

Andalas Univercity, Padang

All Listed Sponsors
collaborator

Andalas University

OTHER

lead

Rahmi Novita Yusuf

OTHER

NCT06604390 - The EFFECTS of GAMBIR CATECHIN (UNCARIA GAMBIR ROXB) SUPPLEMENTATION on COGNITIVE FUNCTION, EXPRESSION of APP, MAPT, BDNF, IL-10, TGF-Β GENES, and PLASMA MDA LEVELS in the ELDERLY. | Biotech Hunter | Biotech Hunter