The Efficacy and Safety of Benmelstobart for GC/EGC

NANot yet recruitingINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

October 16, 2024

Primary Completion Date

July 26, 2026

Study Completion Date

December 26, 2026

Conditions
Gastric Cancer
Interventions
PROCEDURE

surgery

After receiving the corresponding neoadjuvant treatment for 2 cycles, surgery was performed within 3-6 weeks after drug withdrawal.

DRUG

Benmelstobart

1200mg, diluted to 250ml with normal saline, infusion time 60 ± 10mins. The first day of each cycle, 3 weeks (21 days) as a treatment cycle

DRUG

tegafur

it needs to be administered according to the patient\'s body surface area\< 40mg / time at 1.25m2; \> 50mg/ time for 1.25m2 and \<1.5m2; \> 60mg/ time at 1.5m2; Oral, twice a day, after morning and evening meals, for 14 consecutive days, rest for 7 days, as a treatment cycle; Repeat every 3 weeks;

DRUG

oxaliplatin

130mg/m2, administered on the first day of each cycle, repeated every 3 weeks;

DRUG

albumin paclitaxel

260mg/m2, intravenous infusion, 30 minutes per infusion, once every 3 weeks, administered on the first and eighth days of each cycle

All Listed Sponsors
lead

Xijing Hospital

OTHER